| Title |
Management of pemphigus vulgaris: challenges and solutions
|
|---|---|
| Published in |
Clinical, Cosmetic and Investigational Dermatology, October 2015
|
| DOI | 10.2147/ccid.s75908 |
| Pubmed ID | |
| Authors |
Stamatis Gregoriou, Ourania Efthymiou, Christina Stefanaki, Dimitris Rigopoulos |
| Abstract |
The main objective in the treatment of pemphigus vulgaris is to control the disease, prevent relapses, and avoid adverse events associated with the prolonged use of steroids and immunosuppressive agents. Systemic corticosteroids remain the gold standard treatment for pemphigus vulgaris. Azathioprine and mycophenolate mofetil are the first line of steroid-sparing treatment. Rituximab is extremely effective in recalcitrant pemphigus, when other treatments fail to control the disease. The European Dermatology Forum recommends tapering prednisolone by 25% every 2 weeks after the consolidation phase, and a 5 mg reduction every 4 weeks when the dose is reduced to <20 mg. If the patient relapses, options include increasing steroids back to the previous dose, adding an immunosuppressant if using steroid monotherapy, or replacing a first-line immunosuppressant by another if already on combination therapy. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 124 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Unknown | 123 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Postgraduate | 20 | 16% |
| Student > Bachelor | 16 | 13% |
| Student > Master | 15 | 12% |
| Student > Doctoral Student | 12 | 10% |
| Other | 8 | 6% |
| Other | 13 | 10% |
| Unknown | 40 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 63 | 51% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 3% |
| Immunology and Microbiology | 3 | 2% |
| Agricultural and Biological Sciences | 3 | 2% |
| Nursing and Health Professions | 3 | 2% |
| Other | 9 | 7% |
| Unknown | 39 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 January 2024.
All research outputs
#8,091,498
of 25,707,225 outputs
Outputs from Clinical, Cosmetic and Investigational Dermatology
#379
of 916 outputs
Outputs of similar age
#90,396
of 287,669 outputs
Outputs of similar age from Clinical, Cosmetic and Investigational Dermatology
#7
of 14 outputs
Altmetric has tracked 25,707,225 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 916 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 23.0. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 287,669 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.