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Management of the asymptomatic BRCA mutation carrier

Overview of attention for article published in The Application of Clinical Genetics, November 2010
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3 tweeters

Citations

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Readers on

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26 Mendeley
Title
Management of the asymptomatic BRCA mutation carrier
Published in
The Application of Clinical Genetics, November 2010
DOI 10.2147/tacg.s8882
Pubmed ID
Authors

Paige Teller, Rita Munn Kramer, MD

Abstract

Current management of an asymptomatic BRCA mutation carrier includes early initiation and intensive cancer screening in combination with risk reduction strategies. The primary objectives of these interventions are earlier detection and cancer prevention to increase quality of life and prolonged survival. Existing recommendations are often based on the consensus of experts as there are few, supportive, randomized control trials. Management strategies for unaffected patients with BRCA mutations are continually redefined and customized as more evidence-based knowledge is acquired with regard to current intervention efficacy, mutation-related histology, and new treatment modalities. This review provides an outline of current, supported management principles, and interventions in the care of the asymptomatic BRCA mutation carrier. Topics covered include surveillance modalities and risk reduction achieved through behavioral modification, chemoprevention, and prophylactic surgery.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 4%
Unknown 25 96%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 15%
Researcher 3 12%
Other 3 12%
Student > Postgraduate 3 12%
Student > Master 3 12%
Other 6 23%
Unknown 4 15%
Readers by discipline Count As %
Medicine and Dentistry 14 54%
Biochemistry, Genetics and Molecular Biology 4 15%
Agricultural and Biological Sciences 2 8%
Economics, Econometrics and Finance 1 4%
Unknown 5 19%