| Title |
Surgical results and clinical risks of postoperative complications in patients with painful malignant spinal cord compression after decompressive surgery
|
|---|---|
| Published in |
Journal of Pain Research, August 2018
|
| DOI | 10.2147/jpr.s162435 |
| Pubmed ID | |
| Authors |
Shengjie Wang, Yunhao Wang, Zhenghong Yu, Kun Gao, Jia Shao, Ang Li, Yanzheng Gao |
| Abstract |
This study aims to analyze clinical outcome in patients with painful malignant spinal cord compression due to advanced cancers after the decompressive surgery and identify risk factors for postoperative complications in these patients. Furthermore, we created a scoring model to predict the risk of postoperative complications based on identified significant risk factors. We retrospectively analyzed survival outcomes, pain outcomes, and postoperative complications of patients with painful malignant spinal cord compression who were surgically treated in our department. Identification of risk factors for postoperative complications was also performed, and significant factors according to the multiple logistic regression models were included in the scoring model. As a result, 105 patients were enrolled. The overall median survival time was 9.1 months (95% CI, 7.1-11.4 months). The mean worst pain score was 8.0 in a 24-hour period before surgery, while it decreased to 6.0, 5.0, 3.5, 3.3, and 3.6 (all P<0.01, when compared with baseline date) at 1 week, 1 month, 3, 6, and 12 months after surgery, respectively. Similar decreases were also observed in the average pain and the pain interference. Thirty-one complications occurred within 4 weeks after operation in 26 patients (24.8%, 26/105). Based on multiple logistic regression models, age (P=0.03), Karnofsky performance status (P<0.01), and Charlson Comorbidity Index (P=0.04) were significantly associated with postoperative complications and were included in the scoring model. Three risk groups were created based on the complication rates of each scoring points. The corresponding postoperative complication rates of the three groups were 7.7% in group A (0-3 points), 26.7% in group B (4-6 points), and 60.9% in group C (7-10 points), respectively (OR, 4.32, 95% CI: 2.24-8.31, P<0.01). Decompressive surgery for painful malignant spinal cord compression was found to be useful for pain control with a tolerable rate of complications. We created a scoring model to predict the risk of postoperative complications in patients with painful malignant spinal cord compression after surgery. This scoring model may guide doctors to choose the appropriate care strategies to realize better pain management. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 18 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 3 | 17% |
| Student > Ph. D. Student | 2 | 11% |
| Student > Doctoral Student | 1 | 6% |
| Librarian | 1 | 6% |
| Other | 1 | 6% |
| Other | 1 | 6% |
| Unknown | 9 | 50% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 3 | 17% |
| Nursing and Health Professions | 1 | 6% |
| Psychology | 1 | 6% |
| Neuroscience | 1 | 6% |
| Materials Science | 1 | 6% |
| Other | 1 | 6% |
| Unknown | 10 | 56% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 August 2018.
All research outputs
#18,648,325
of 23,102,082 outputs
Outputs from Journal of Pain Research
#1,414
of 1,773 outputs
Outputs of similar age
#254,555
of 331,050 outputs
Outputs of similar age from Journal of Pain Research
#50
of 58 outputs
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We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.