Title |
Insight into Acinetobacter baumannii: pathogenesis, global resistance, mechanisms of resistance, treatment options, and alternative modalities
|
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Published in |
Infection and Drug Resistance, August 2018
|
DOI | 10.2147/idr.s166750 |
Pubmed ID | |
Authors |
Muhammad Asif, Iqbal Ahmad Alvi, Shafiq Ur Rehman |
Abstract |
Acinetobacter baumannii, once considered a low-category pathogen, has emerged as an obstinate infectious agent. The scientific community is paying more attention to this pathogen due to its stubbornness to last resort antimicrobials, including carbapenems, colistin, and tigecycline, its high prevalence of infections in the hospital setting, and significantly increased rate of community-acquired infections by this organism over the past decade. It has given the fear of pre-antibiotic era to the world. To further enhance our understanding about this pathogen, in this review, we discuss its taxonomy, pathogenesis, current treatment options, global resistance rates, mechanisms of its resistance against various groups of antimicrobials, and future therapeutics. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 4 | 31% |
Pakistan | 1 | 8% |
Venezuela, Bolivarian Republic of | 1 | 8% |
Mexico | 1 | 8% |
Niger | 1 | 8% |
Malaysia | 1 | 8% |
Unknown | 4 | 31% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 11 | 85% |
Practitioners (doctors, other healthcare professionals) | 2 | 15% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 567 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 96 | 17% |
Student > Master | 81 | 14% |
Student > Ph. D. Student | 51 | 9% |
Student > Postgraduate | 40 | 7% |
Researcher | 33 | 6% |
Other | 67 | 12% |
Unknown | 199 | 35% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 101 | 18% |
Immunology and Microbiology | 78 | 14% |
Medicine and Dentistry | 67 | 12% |
Agricultural and Biological Sciences | 41 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 14 | 2% |
Other | 57 | 10% |
Unknown | 209 | 37% |