| Title |
Optimal management of steroid-dependent ulcerative colitis
|
|---|---|
| Published in |
Clinical and Experimental Gastroenterology, November 2015
|
| DOI | 10.2147/ceg.s57248 |
| Pubmed ID | |
| Authors |
Hafiz M Waqas Khan, Faisal Mehmood, Nabeel Khan |
| Abstract |
Ulcerative colitis (UC) is a chronic inflammatory condition that is variable in both extent and severity of disease as well as response to therapy. Corticosteroids (CSs) were the first drugs used in the management of UC and are still used for induction of remission. However, because of their extensive side-effect profile, they are not utilized for maintenance of remission. In view of this, CS-free remission has become an important end point while evaluating therapeutic agents used in the management of UC. This review highlights the results of various studies conducted to evaluate the efficacy of different medications to attain CS-free remission in the setting of active UC. The drugs reviewed include established agents such as thiopurines, methotrexate, infliximab, adalimumab, vedolizumab, golimumab, and newer experimental agents, and if all else fails, colectomy will be performed. The efficacy of these drugs is evaluated individually. Our aim is to provide a synopsis of the work done in this field to date. |
Mendeley readers
The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 63 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 9 | 14% |
| Researcher | 7 | 11% |
| Student > Master | 6 | 10% |
| Other | 5 | 8% |
| Student > Postgraduate | 5 | 8% |
| Other | 12 | 19% |
| Unknown | 19 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 22 | 35% |
| Unspecified | 3 | 5% |
| Biochemistry, Genetics and Molecular Biology | 3 | 5% |
| Arts and Humanities | 2 | 3% |
| Nursing and Health Professions | 2 | 3% |
| Other | 10 | 16% |
| Unknown | 21 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 January 2021.
All research outputs
#5,503,217
of 25,576,275 outputs
Outputs from Clinical and Experimental Gastroenterology
#84
of 330 outputs
Outputs of similar age
#68,503
of 295,307 outputs
Outputs of similar age from Clinical and Experimental Gastroenterology
#4
of 4 outputs
Altmetric has tracked 25,576,275 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 330 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.5. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 295,307 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.