So why isn’t $ALDX a better bet on Geographic Atrophy long term therapy than is C5 $ISEE inhibition? Harvard didn’t back them. Nature says there are many explanations for GA - merely end stage result of any MOA. $ALDX targets best instigator- Aldehydes.
RT @TonyFauci2: $ALDX / Harvard - Lipofuscin stimulates Geographic Atrophy via Aldehyde payload of LIpofuscin- trapping it ameliorates RPE…
$ALDX / Harvard - Lipofuscin stimulates Geographic Atrophy via Aldehyde payload of LIpofuscin- trapping it ameliorates RPE damage. ADX 248. https://t.co/MXGlYRWahZ
$ALDX unique trapping of the one visible correlate of GA and AMD - promises to stop disease progression rather than just slowing it- $APLS $ISEE
RT @TonyFauci2: If you haven’t looked into Lipofuscin- don’t buy or sell $ALDX - ophthalmic education required. GA $ISEE $APLS
If you haven’t looked into Lipofuscin- don’t buy or sell $ALDX - ophthalmic education required. GA $ISEE $APLS
“Increased autofluorescence surrounding the area of GA has been sug- gested to be a risk factor for progression” https://t.co/viJQEVbAB1 Harvard- Autoflourescence is Aldehyde based https://t.co/sv1ws0YVEj SO $ALDX ADX-248 reduces Aldehydes, Autoflourescenc
RT @TonyFauci2: “Lipofuscin from photoreceptor outer segments via reactions with vit A aldehyde-An important observation associated w/devel…
“Lipofuscin from photoreceptor outer segments via reactions with vit A aldehyde-An important observation associated w/development of GA is autofluorescence assocd w/accumulation of lipofuscin w/ age -predicts development of GA” https://t.co/Ga0B5xVlLU $ALD
RT @OCTMD: Geographic atrophy in patients with advanced dry age-related macular degeneration: current challenges and future p… https://t.co…
RT @OCTMD: Geographic atrophy in patients with advanced dry age-related macular degeneration: current challenges and future p… https://t.co…
Geographic atrophy in patients with advanced dry age-related macular degeneration: current challenges and future p… https://t.co/VYvIVE7qQt
Geographic atrophy https://t.co/Ff1cKM7sRI