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Novel platinum–palladium bimetallic nanoparticles synthesized by Dioscorea bulbifera: anticancer and antioxidant activities

Overview of attention for article published in International Journal of Nanomedicine, December 2015
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Mentioned by

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3 tweeters

Citations

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89 Dimensions

Readers on

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113 Mendeley
Title
Novel platinum–palladium bimetallic nanoparticles synthesized by Dioscorea bulbifera: anticancer and antioxidant activities
Published in
International Journal of Nanomedicine, December 2015
DOI 10.2147/ijn.s91579
Pubmed ID
Authors

Balu Chopade, Sougata Ghosh, Rahul Nitnavare, Ankush Dewle, Geetanjali B. Tomar, Rohan Chippalkatti, Piyush More, Rohini Kitture, Sangeeta Kale, Jayesh Bellare

Abstract

Medicinal plants serve as rich sources of diverse bioactive phytochemicals that might even take part in bioreduction and stabilization of phytogenic nanoparticles with immense therapeutic properties. Herein, we report for the first time the rapid efficient synthesis of novel platinum-palladium bimetallic nanoparticles (Pt-PdNPs) along with individual platinum (PtNPs) and palladium (PdNPs) nanoparticles using a medicinal plant, Dioscorea bulbifera tuber extract (DBTE). High-resolution transmission electron microscopy revealed monodispersed PtNPs of size 2-5 nm, while PdNPs and Pt-PdNPs between 10 and 25 nm. Energy dispersive spectroscopy analysis confirmed 30.88%±1.73% elemental Pt and 68.96%±1.48% elemental Pd in the bimetallic nanoparticles. Fourier transform infrared spectra indicated strong peaks at 3,373 cm(-1), attributed to hydroxyl group of polyphenolic compounds in DBTE that might play a key role in bioreduction in addition to the sharp peaks at 2,937, 1,647, 1,518, and 1,024 cm(-1), associated with C-H stretching, N-H bending in primary amines, N-O stretching in nitro group, and C-C stretch, respectively. Anticancer activity against HeLa cells showed that Pt-PdNPs exhibited more pronounced cell death of 74.25% compared to individual PtNPs (12.6%) or PdNPs (33.15%). Further, Pt-PdNPs showed an enhanced scavenging activity against 2,2-diphenyl-1-picrylhydrazyl, superoxide, nitric oxide, and hydroxyl radicals.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 113 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 <1%
Portugal 1 <1%
France 1 <1%
South Africa 1 <1%
Unknown 109 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 26 23%
Student > Bachelor 12 11%
Student > Master 11 10%
Student > Doctoral Student 9 8%
Other 8 7%
Other 19 17%
Unknown 28 25%
Readers by discipline Count As %
Chemistry 17 15%
Biochemistry, Genetics and Molecular Biology 12 11%
Agricultural and Biological Sciences 10 9%
Materials Science 5 4%
Pharmacology, Toxicology and Pharmaceutical Science 5 4%
Other 27 24%
Unknown 37 33%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2015.
All research outputs
#5,210,753
of 9,728,122 outputs
Outputs from International Journal of Nanomedicine
#822
of 2,076 outputs
Outputs of similar age
#142,711
of 301,429 outputs
Outputs of similar age from International Journal of Nanomedicine
#52
of 82 outputs
Altmetric has tracked 9,728,122 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,076 research outputs from this source. They receive a mean Attention Score of 2.9. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 301,429 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 82 others from the same source and published within six weeks on either side of this one. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.