Title |
Diagnosis and treatment of diarrhea-predominant irritable bowel syndrome
|
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Published in |
International Journal of General Medicine, February 2016
|
DOI | 10.2147/ijgm.s93698 |
Pubmed ID | |
Authors |
Brian E Lacy |
Abstract |
Irritable bowel syndrome (IBS) is one of the most common gastrointestinal disorders worldwide. The economic impact of IBS on the health care system is substantial, as is the personal impact on patients. Patients with diarrhea-predominant IBS (IBS-D) comprise a substantial proportion of the overall IBS population. Primary care providers are often the first point of contact for patients with IBS-D and can accurately diagnose IBS after a careful history and examination without extensive diagnostic tests. Several pharmacologic treatments (eg, loperamide, alosetron, and antidepressants) and non-pharmacologic treatments (eg, dietary modification and probiotics) are available for IBS-D, but restrictions on use (eg, alosetron) or the lack of controlled trial data showing reductions in both global and individual IBS-D symptoms (eg, bloating, pain and stool frequency) emphasize the need for alternative treatment options. Two newer medications (eluxadoline and rifaximin) were approved in May 2015 for the treatment of IBS-D, and represent new treatment options for this common gastrointestinal condition. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 33% |
United Kingdom | 1 | 33% |
Canada | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 2 | 67% |
Members of the public | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 109 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 21 | 19% |
Student > Master | 13 | 12% |
Researcher | 12 | 11% |
Other | 10 | 9% |
Student > Ph. D. Student | 8 | 7% |
Other | 18 | 17% |
Unknown | 27 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 40 | 37% |
Agricultural and Biological Sciences | 8 | 7% |
Biochemistry, Genetics and Molecular Biology | 7 | 6% |
Nursing and Health Professions | 7 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 6 | 6% |
Other | 9 | 8% |
Unknown | 32 | 29% |