Title |
Childhood neuroblastoma masquerading as pheochromocytoma: case report
|
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Published in |
International Medical Case Reports Journal, March 2016
|
DOI | 10.2147/imcrj.s100479 |
Pubmed ID | |
Authors |
Suk-Bae Moon |
Abstract |
Neuroblastoma is the most common extracranial solid tumor in children. Mild hypertension is a frequent symptom, presumably an effect of catecholamines that tumors release. Reported herein is the rare occurrence of severe hypertension and subsequent heart failure attributable to adrenal gland neuroblastoma. A 3-year-old boy presented with anterior chest wall protrusion. Physical examination revealed severe hypertension, and left-sided cardiac failure was evident by echocardiography. Catecholamine metabolite (norepinephrine) levels were increased in serum (>2,000 pg/mL) and in urine (1,350.5 µg/day). Abdominal computed tomography scan showed a 7 cm solid mass arising from right adrenal gland. Oral phenoxybenzamine was given for hemodynamic stabilization, and right adrenalectomy was performed to remove an apparent pheochromocytoma. Ultimately, the pathologic diagnosis was ganglioneuroblastoma. Both hypertension and cardiac failure resolved postoperatively. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 25 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 5 | 20% |
Student > Master | 4 | 16% |
Student > Bachelor | 3 | 12% |
Professor | 2 | 8% |
Student > Doctoral Student | 1 | 4% |
Other | 3 | 12% |
Unknown | 7 | 28% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 11 | 44% |
Biochemistry, Genetics and Molecular Biology | 2 | 8% |
Agricultural and Biological Sciences | 2 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
Engineering | 1 | 4% |
Other | 0 | 0% |
Unknown | 8 | 32% |