Title |
Does amantadine induce acute psychosis? A case report and literature review
|
---|---|
Published in |
Neuropsychiatric Disease and Treatment, April 2016
|
DOI | 10.2147/ndt.s101569 |
Pubmed ID | |
Authors |
Wei-juan Xu, Ning Wei, Yi Xu, Shao-hua Hu |
Abstract |
Over-the-counter cold medicines, which contain amantadine, are widely used in the People's Republic of China. Clinicians are familiar with the psychosis caused by long-term treatment with amantadine, especially in elderly patients; however, early-onset psychotic complications among healthy young individuals have rarely been reported. This article reports the case of a 28-year-old patient who presented with hallucination-delusion syndrome soon after treatment with cold medicine containing amantadine hydrochloride and acetaminophen. The symptoms resolved completely after a 2-week course of paliperidone treatment. Clinicians should be sensitive to the acute psychotic complications induced by an interaction between amantadine and acetaminophen. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 5% |
Unknown | 20 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 4 | 19% |
Student > Master | 2 | 10% |
Student > Bachelor | 2 | 10% |
Unspecified | 1 | 5% |
Other | 1 | 5% |
Other | 2 | 10% |
Unknown | 9 | 43% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 5 | 24% |
Psychology | 3 | 14% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 5% |
Chemistry | 1 | 5% |
Unspecified | 1 | 5% |
Other | 0 | 0% |
Unknown | 10 | 48% |