| Title |
Evidence of functional declining and global comorbidity measured at baseline proved to be the strongest predictors for long-term death in elderly community residents aged 85 years: a 5-year follow-up evaluation, the OCTABAIX study
|
|---|---|
| Published in |
Clinical Interventions in Aging, April 2016
|
| DOI | 10.2147/cia.s101447 |
| Pubmed ID | |
| Authors |
Francesc Formiga, Assumpta Ferrer, Gloria Padros, Abelardo Montero, Carme Gimenez-Argente, Xavier Corbella |
| Abstract |
To investigate the predictive value of functional impairment, chronic conditions, and laboratory biomarkers of aging for predicting 5-year mortality in the elderly aged 85 years. Predictive value for mortality of different geriatric assessments carried out during the OCTABAIX study was evaluated after 5 years of follow-up in 328 subjects aged 85 years. Measurements included assessment of functional status comorbidity, along with laboratory tests on vitamin D, cholesterol, CD4/CD8 ratio, hemoglobin, and serum thyrotropin. Overall, the mortality rate after 5 years of follow-up was 42.07%. Bivariate analysis showed that patients who survived were predominantly female (P=0.02), and they showed a significantly better baseline functional status for both basic (P<0.001) and instrumental (P<0.001) activities of daily living (Barthel and Lawton index), better cognitive performance (Spanish version of the Mini-Mental State Examination) (P<0.001), lower comorbidity conditions (Charlson) (P<0.001), lower nutritional risk (Mini Nutritional Assessment) (P<0.001), lower risk of falls (Tinetti gait scale) (P<0.001), less percentage of heart failure (P=0.03) and chronic obstructive pulmonary disease (P=0.03), and took less chronic prescription drugs (P=0.002) than nonsurvivors. Multivariate Cox regression analysis identified a decreased score in the Lawton index (hazard ratio 0.86, 95% confidence interval: 0.78-0.91) and higher comorbidity conditions (hazard ratio 1.20, 95% confidence interval: 1.08-1.33) as independent predictors of mortality at 5 years in the studied population. The ability to perform instrumental activities of daily living and the global comorbidity assessed at baseline were the predictors of death, identified in our 85-year-old community-dwelling subjects after 5 years of follow-up. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 3 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 2 | 67% |
| Members of the public | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 115 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | <1% |
| Portugal | 1 | <1% |
| Unknown | 113 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 26 | 23% |
| Student > Bachelor | 16 | 14% |
| Student > Ph. D. Student | 10 | 9% |
| Student > Doctoral Student | 7 | 6% |
| Student > Postgraduate | 7 | 6% |
| Other | 15 | 13% |
| Unknown | 34 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 36 | 31% |
| Nursing and Health Professions | 21 | 18% |
| Agricultural and Biological Sciences | 5 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
| Immunology and Microbiology | 2 | 2% |
| Other | 8 | 7% |
| Unknown | 41 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 May 2016.
All research outputs
#3,415,054
of 25,373,627 outputs
Outputs from Clinical Interventions in Aging
#370
of 1,968 outputs
Outputs of similar age
#52,992
of 314,719 outputs
Outputs of similar age from Clinical Interventions in Aging
#8
of 53 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
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We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.