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Dove Medical Press

BC200 LncRNA a potential predictive marker of poor prognosis in esophageal squamous cell carcinoma patients

Overview of attention for article published in OncoTargets and therapy, April 2016
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (54th percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

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1 Wikipedia page

Citations

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27 Dimensions

Readers on

mendeley
19 Mendeley
Title
BC200 LncRNA a potential predictive marker of poor prognosis in esophageal squamous cell carcinoma patients
Published in
OncoTargets and therapy, April 2016
DOI 10.2147/ott.s99401
Pubmed ID
Authors

Rui-Hua Zhao, Cai-hua Zhu, Xiang-Ke Li, Wei Cao, Hong Zong, Xin-Guang Cao, Hai-Yan Hu

Abstract

To explore the expression and prognosis significance of BC200 in esophageal squamous cell carcinoma (ESCC) patients who received radical resection. We used quantitative real-time polymerase chain reaction to detect the expression level of BC200 in cancer tissue and paired adjacent normal tissue samples from 70 ESCC patients who received radical surgical resection and analyzed the correlation of the relative expression level of BC200 with clinical-pathological features and prognosis. We found that the relative expression of BC200 was significantly higher in ESCC tissues compared with adjacent normal tissue samples (P=0.023). But the expression of BC200 were not related to clinical-pathological features, such as age, TNM stages, and histological grade (P>0.05). Kaplan-Meier analysis showed that high expression levels of BC200 were correlated with poor prognosis in ESCC patients. Patients with a high level of BC200 had a shorter disease-free survival and overall survival than those with low BC200 expression (P=0.034 and P=0.031, respectively). On multivariate analysis, the hazard ratio (HR) of BC200 expression was 2.17 (95% confidence interval [CI]=1.12-4.19, P=0.022) for disease-free survival and 2.24 (95% CI=1.12-4.49, P=0.023) for overall survival. Our results indicate that high expression of BC200 reflects poor prognosis and could serve as a novel predictive marker for ESCC patients who received radical resection.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 26%
Student > Ph. D. Student 5 26%
Student > Doctoral Student 2 11%
Lecturer 1 5%
Student > Bachelor 1 5%
Other 2 11%
Unknown 3 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 9 47%
Medicine and Dentistry 3 16%
Neuroscience 2 11%
Psychology 1 5%
Agricultural and Biological Sciences 1 5%
Other 1 5%
Unknown 2 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 May 2018.
All research outputs
#8,534,528
of 25,371,288 outputs
Outputs from OncoTargets and therapy
#547
of 3,016 outputs
Outputs of similar age
#115,146
of 314,719 outputs
Outputs of similar age from OncoTargets and therapy
#25
of 128 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,016 research outputs from this source. They receive a mean Attention Score of 2.9. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 314,719 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.
We're also able to compare this research output to 128 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.