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Altered intrinsic regional brain spontaneous activity in patients with comitant strabismus: a resting-state functional MRI study

Overview of attention for article published in Neuropsychiatric Disease and Treatment, June 2016
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Title
Altered intrinsic regional brain spontaneous activity in patients with comitant strabismus: a resting-state functional MRI study
Published in
Neuropsychiatric Disease and Treatment, June 2016
DOI 10.2147/ndt.s105478
Pubmed ID
Authors

Xin Huang, Sheng-Hong Li, Fu-Qing Zhou, Ying Zhang, Yu-Lin Zhong, Feng-Qin Cai, Yi Shao, Xian-Jun Zeng

Abstract

To investigate the underlying regional homogeneity (ReHo) of brain-activity abnormalities in patients with comitant strabismus (CS) and their relationship with behavioral performance. Twenty patients with CS (ten men and ten women) and 20 (ten men and ten women) age-, sex-, and education-matched healthy controls (HCs) underwent resting-state functional magnetic resonance imaging scans. The ReHo method was used to assess local features of spontaneous brain activities. Patients with CS were distinguished from HCs by receiver operating characteristic curve. Correlation analysis was performed to explore the relationship between the observed mean ReHo values of the different brain areas and behavioral performance. Compared to HCs, the patients with CS showed significantly increased ReHo values in the right inferior temporal cortex/fusiform gyrus/cerebellum anterior lobe, right lingual gyrus, and bilateral cingulate gyrus. We did not find any relationship between the observed mean ReHo values of the different brain areas and behavioral performance. CS causes dysfunction in many brain regions, which may explain the fusion compensation in CS.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 11 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 27%
Other 2 18%
Student > Master 1 9%
Researcher 1 9%
Student > Postgraduate 1 9%
Other 0 0%
Unknown 3 27%
Readers by discipline Count As %
Medicine and Dentistry 5 45%
Neuroscience 2 18%
Engineering 1 9%
Unknown 3 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 June 2016.
All research outputs
#17,285,668
of 25,373,627 outputs
Outputs from Neuropsychiatric Disease and Treatment
#1,902
of 3,132 outputs
Outputs of similar age
#225,301
of 353,659 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#66
of 94 outputs
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