Title |
Role of adalimumab in the management of children and adolescents with juvenile idiopathic arthritis and other rheumatic conditions
|
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Published in |
Adolescent Health, Medicine and Therapeutics, June 2012
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DOI | 10.2147/ahmt.s22607 |
Pubmed ID | |
Authors |
Katherine Anne B Marzan |
Abstract |
Treatment of children and adolescents with juvenile idiopathic arthritis and other pediatric rheumatic diseases has evolved. Where once there was only a limited arsenal of medications, with significant side effects and inadequate efficacy, today, with an increased understanding of the pathogenesis of these diseases, there is a wider variety of more targeted and effective treatments. TNF-α is a cytokine involved in a number of inflammatory pathways in pediatric rheumatic diseases. The emergence of biologic modifiers that target TNF-α has been pivotal in providing the ability to deliver early and aggressive treatment. Adalimumab, a recombinant monoclonal antibody to TNF-α, is an important therapeutic option, which affords children and adolescents with chronic illnesses an improved quality of life. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 1 | 2% |
Unknown | 48 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 9 | 18% |
Student > Ph. D. Student | 8 | 16% |
Student > Bachelor | 6 | 12% |
Other | 5 | 10% |
Researcher | 4 | 8% |
Other | 7 | 14% |
Unknown | 10 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 27 | 55% |
Agricultural and Biological Sciences | 3 | 6% |
Biochemistry, Genetics and Molecular Biology | 2 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
Computer Science | 1 | 2% |
Other | 3 | 6% |
Unknown | 12 | 24% |