| Title |
Vascular involvement in systemic sclerosis (scleroderma)
|
|---|---|
| Published in |
Journal of Inflammation Research, July 2011
|
| DOI | 10.2147/jir.s18145 |
| Pubmed ID | |
| Authors |
Debendra Pattanaik, Monica Brown, Arnold E Postlethwaite |
| Abstract |
Systemic sclerosis (SSc) is an acquired multiorgan connective tissue disease with variable mortality and morbidity dictated by clinical subset type. The etiology of the basic disease and pathogenesis of the systemic autoimmunity, fibrosis, and fibroproliferative vasculopathy are unknown and debated. In this review, the spectrum of vascular abnormalities and the options currently available to treat the vascular manifestations of SSc are discussed. Also discussed is how the hallmark pathologies (ie, how autoimmunity, vasculopathy, and fibrosis of the disease) might be effected and interconnected with modulatory input from lysophospholipids, sphingosine 1-phosphate, and lysophosphatidic acid. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 1% |
| Egypt | 1 | 1% |
| Unknown | 86 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Doctoral Student | 13 | 15% |
| Student > Master | 11 | 13% |
| Other | 10 | 11% |
| Student > Ph. D. Student | 9 | 10% |
| Researcher | 8 | 9% |
| Other | 12 | 14% |
| Unknown | 25 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 33 | 38% |
| Agricultural and Biological Sciences | 10 | 11% |
| Immunology and Microbiology | 7 | 8% |
| Biochemistry, Genetics and Molecular Biology | 4 | 5% |
| Engineering | 3 | 3% |
| Other | 7 | 8% |
| Unknown | 24 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 November 2011.
All research outputs
#15,978,853
of 25,373,627 outputs
Outputs from Journal of Inflammation Research
#312
of 974 outputs
Outputs of similar age
#88,849
of 127,138 outputs
Outputs of similar age from Journal of Inflammation Research
#1
of 1 outputs
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