| Title |
Mirabegron – a selective ß3-adrenoreceptor agonist for the treatment of overactive bladder
|
|---|---|
| Published in |
Research and Reports in Urology, July 2012
|
| DOI | 10.2147/rru.s28930 |
| Pubmed ID | |
| Authors |
Alka A Bhide, G Alessandro Digesu, Ruwan Fernando, Vik Khullar |
| Abstract |
Overactive bladder is a common condition that significantly impacts overall quality of life. Antimuscarinics are the current main pharmacological option for treatment; however, many patients fail to adhere to therapy due to troublesome side effects. Mirabegron is a new beta-3 adrenoreceptor agonist which causes detrusor smooth muscle relaxation and has been proposed to be effective for treating overactive bladder symptoms. Mirabegron has been shown to be superior to placebo for reducing the mean number of incontinence episodes per 24 hours and the mean number of micturitions per 24 hours. Side effects such as dry mouth were observed at similar or lower rates than those seen for placebo and antimuscarinics. Higher doses of mirabegron were associated with minor increases in pulse rate and mean blood pressure. Mirabegron offers a new alternative for treating overactive bladder in patients for which antimuscarinics are either not tolerated or not appropriate. |
Mendeley readers
The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 22 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 3 | 14% |
| Other | 2 | 9% |
| Researcher | 2 | 9% |
| Lecturer | 1 | 5% |
| Professor | 1 | 5% |
| Other | 3 | 14% |
| Unknown | 10 | 45% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 6 | 27% |
| Agricultural and Biological Sciences | 2 | 9% |
| Arts and Humanities | 1 | 5% |
| Nursing and Health Professions | 1 | 5% |
| Environmental Science | 1 | 5% |
| Other | 2 | 9% |
| Unknown | 9 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 December 2013.
All research outputs
#7,229,557
of 23,577,654 outputs
Outputs from Research and Reports in Urology
#75
of 233 outputs
Outputs of similar age
#50,121
of 165,006 outputs
Outputs of similar age from Research and Reports in Urology
#1
of 2 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 233 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.7. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 165,006 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them