| Title |
Berberine hydrochloride: anticancer activity and nanoparticulate delivery system
|
|---|---|
| Published in |
International Journal of Nanomedicine, August 2011
|
| DOI | 10.2147/ijn.s22683 |
| Pubmed ID | |
| Authors |
Wen Tan, Yingbo Li, Meiwan Chen, Yitao Wang |
| Abstract |
Berberine hydrochloride is a conventional component in Chinese medicine, and is characterized by a diversity of pharmacological effects. However, due to its hydrophobic properties, along with poor stability and bioavailability, the application of berberine hydrochloride was hampered for a long time. In recent years, the pharmaceutical preparation of berberine hydrochloride has improved to achieve good prospects for clinical application, especially for novel nanoparticulate delivery systems. Moreover, anticancer activity and novel mechanisms have been explored, the chance of regulating glucose and lipid metabolism in cancer cells showing more potential than ever. Therefore, it is expected that appropriate pharmaceutical procedures could be applied to the enormous potential for anticancer efficacy, to give some new insights into anticancer drug preparation in Chinese medicine. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 114 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 2 | 2% |
| Japan | 1 | <1% |
| United States | 1 | <1% |
| Malaysia | 1 | <1% |
| Unknown | 109 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 18% |
| Student > Master | 18 | 16% |
| Student > Bachelor | 13 | 11% |
| Researcher | 12 | 11% |
| Other | 7 | 6% |
| Other | 14 | 12% |
| Unknown | 30 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Pharmacology, Toxicology and Pharmaceutical Science | 21 | 18% |
| Biochemistry, Genetics and Molecular Biology | 16 | 14% |
| Medicine and Dentistry | 16 | 14% |
| Agricultural and Biological Sciences | 10 | 9% |
| Chemistry | 8 | 7% |
| Other | 9 | 8% |
| Unknown | 34 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 January 2015.
All research outputs
#17,286,379
of 25,374,917 outputs
Outputs from International Journal of Nanomedicine
#2,470
of 4,123 outputs
Outputs of similar age
#93,377
of 130,326 outputs
Outputs of similar age from International Journal of Nanomedicine
#34
of 38 outputs
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