Title |
Suppression of lung cancer progression by biocompatible glycerol triacrylate– spermine-mediated delivery of shAkt1
|
---|---|
Published in |
International Journal of Nanomedicine, May 2012
|
DOI | 10.2147/ijn.s29152 |
Pubmed ID | |
Authors |
Seong-Ho Hong, Ji-Eun Kim, You-Kyoung Kim, Arash Minai-Tehrani, Ji-Young Shin, Bitna Kang, Hye-Joon Kim, Chong-Su Cho, Chanhee Chae, Hu-Lin Jiang, Myung-Haing Cho |
Abstract |
Polyethylenimine (PEI)-based nonviral gene-delivery systems are commonly employed because of their high transfection efficiency. However, the toxic nature of PEI is a significant obstacle in clinical gene therapy. In this study, we developed biocompatible glycerol triacrylate-spermine (GT-SPE) polyspermine as a nanosized gene carrier for potential lung cancer gene therapy. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 23 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 5 | 22% |
Student > Ph. D. Student | 5 | 22% |
Student > Doctoral Student | 2 | 9% |
Student > Bachelor | 2 | 9% |
Professor | 2 | 9% |
Other | 4 | 17% |
Unknown | 3 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 17% |
Medicine and Dentistry | 4 | 17% |
Computer Science | 3 | 13% |
Biochemistry, Genetics and Molecular Biology | 2 | 9% |
Materials Science | 2 | 9% |
Other | 5 | 22% |
Unknown | 3 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 May 2012.
All research outputs
#17,438,425
of 25,584,565 outputs
Outputs from International Journal of Nanomedicine
#2,461
of 4,077 outputs
Outputs of similar age
#115,719
of 176,069 outputs
Outputs of similar age from International Journal of Nanomedicine
#52
of 66 outputs
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So far Altmetric has tracked 4,077 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
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We're also able to compare this research output to 66 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.