Title |
Adjunctive therapy in Parkinson's disease: the role of rasagiline
|
---|---|
Published in |
Neuropsychiatric Disease and Treatment, July 2012
|
DOI | 10.2147/ndt.s25142 |
Pubmed ID | |
Authors |
Kathryn D Gaines, Vanessa K Hinson |
Abstract |
Parkinson's disease is the second most common neurodegenerative disorder, currently affecting 1.5 million people in the US. In this review, we describe the diagnostic and pathological features of Parkinson's disease, as well as its clinical course. We then review pharmacologic treatments for the disease, with a particular focus on therapies adjunctive to levodopa and specifically the role of rasagiline. We review the four pivotal rasagiline trials, and discuss rasagiline and its use as adjunctive therapy for Parkinson's disease. Finally, we discuss potential side effects, drug interactions, and other practical aspects concerning the use of rasagiline in Parkinson's disease. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 1 | 3% |
Unknown | 38 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 11 | 28% |
Student > Master | 6 | 15% |
Student > Ph. D. Student | 5 | 13% |
Other | 4 | 10% |
Student > Bachelor | 4 | 10% |
Other | 5 | 13% |
Unknown | 4 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 11 | 28% |
Agricultural and Biological Sciences | 8 | 21% |
Psychology | 8 | 21% |
Neuroscience | 3 | 8% |
Biochemistry, Genetics and Molecular Biology | 1 | 3% |
Other | 3 | 8% |
Unknown | 5 | 13% |