Title |
Hepatocellular carcinoma: current trends in worldwide epidemiology, risk factors, diagnosis, and therapeutics
|
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Published in |
Hepatic medicine evidence and research, May 2012
|
DOI | 10.2147/hmer.s16316 |
Pubmed ID | |
Authors |
Renumathy Dhanasekaran, Alpna Limaye, Roniel Cabrera |
Abstract |
Hepatocellular carcinoma (HCC) is a common malignancy in developing countries and its incidence is on the rise in the developing world. The epidemiology of this cancer is unique since its risk factors, including hepatitis C and B, have been clearly established. The current trends in the shifting incidence of HCC in different regions of the world can be explained partly by the changing prevalence of hepatitis. Early detection offers the only hope for curative treatment for patients with HCC, hence effective screening strategies for high-risk patients is of utmost importance. Liver transplantation and surgical resection remains the cornerstone of curative treatment. But major advances in locoregional therapies and molecular-targeted therapies for the treatment of advanced HCC have occurred recently. In this review, current trends in the worldwide epidemiology, surveillance, diagnosis, standard treatments, and the emerging therapies for HCC are discussed. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 1% |
Japan | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 191 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 35 | 18% |
Student > Master | 32 | 16% |
Student > Bachelor | 17 | 9% |
Student > Ph. D. Student | 16 | 8% |
Student > Doctoral Student | 14 | 7% |
Other | 42 | 22% |
Unknown | 39 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 69 | 35% |
Biochemistry, Genetics and Molecular Biology | 28 | 14% |
Agricultural and Biological Sciences | 28 | 14% |
Chemistry | 5 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 3% |
Other | 14 | 7% |
Unknown | 46 | 24% |