| Title |
Amyotrophic lateral sclerosis: update and new developments
|
|---|---|
| Published in |
Degenerative Neurological and Neuromuscular Disease, February 2012
|
| DOI | 10.2147/dnnd.s19803 |
| Pubmed ID | |
| Authors |
Ashley J Pratt, Elizabeth D Getzoff, J Jefferson P Perry |
| Abstract |
Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease. It is typically characterized by adult-onset degeneration of the upper and lower motor neurons, and is usually fatal within a few years of onset. A subset of ALS patients has an inherited form of the disease, and a few of the known mutant genes identified in familial cases have also been found in sporadic forms of ALS. Precisely how the diverse ALS-linked gene products dictate the course of the disease, resulting in compromised voluntary muscular ability, is not entirely known. This review addresses the major advances that are being made in our understanding of the molecular mechanisms giving rise to the disease, which may eventually translate into new treatment options. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 136 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 1% |
| Australia | 1 | <1% |
| Korea, Republic of | 1 | <1% |
| South Africa | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 130 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 27 | 20% |
| Student > Ph. D. Student | 26 | 19% |
| Student > Master | 20 | 15% |
| Researcher | 19 | 14% |
| Student > Postgraduate | 12 | 9% |
| Other | 17 | 13% |
| Unknown | 15 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 36 | 26% |
| Medicine and Dentistry | 34 | 25% |
| Biochemistry, Genetics and Molecular Biology | 15 | 11% |
| Neuroscience | 10 | 7% |
| Psychology | 5 | 4% |
| Other | 16 | 12% |
| Unknown | 20 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 April 2020.
All research outputs
#3,661,761
of 25,584,565 outputs
Outputs from Degenerative Neurological and Neuromuscular Disease
#22
of 89 outputs
Outputs of similar age
#28,598
of 254,308 outputs
Outputs of similar age from Degenerative Neurological and Neuromuscular Disease
#1
of 1 outputs
Altmetric has tracked 25,584,565 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 89 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.9. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 254,308 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them