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Clinical utility of clocortolone pivalate for the treatment of corticosteroid-responsive skin disorders: a systematic review

Overview of attention for article published in Clinical, Cosmetic and Investigational Dermatology, June 2012
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Mentioned by

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1 tweeter

Citations

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4 Dimensions

Readers on

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12 Mendeley
Title
Clinical utility of clocortolone pivalate for the treatment of corticosteroid-responsive skin disorders: a systematic review
Published in
Clinical, Cosmetic and Investigational Dermatology, June 2012
DOI 10.2147/ccid.s23227
Pubmed ID
Authors

Sanjay Singh, Mann

Abstract

Clocortolone pivalate 0.1% cream is a class IV mid-strength topical glucocorticoid. After topical application the glucocorticoid achieves higher concentration in inflamed skin compared with normal skin. Furthermore, pharmacologic studies have shown that there is little systemic absorption of clocortolone pivalate and hence no adrenal suppression. Systematic review was performed to evaluate the efficacy and safety of the glucocorticoid. PubMed, the Cochrane Library, and individual websites of the top 20 dermatology journals were searched using a defined strategy. Following the selection criteria, eight clinical trials were selected, of which five were randomized controlled trials. The trials mainly included patients with atopic dermatitis and eczemas. Quality appraisal of randomized controlled trials was done using the Delphi list, which showed that the trials had weaknesses in several items. The results of the systematic review tend to show that clocortolone pivalate cream is generally effective with early onset of action and has a good safety profile in the treatment of these conditions. Further studies comparing this glucocorticoid with other glucocorticoids and treatments in steroid-responsive dermatoses are desirable.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 33%
Student > Ph. D. Student 2 17%
Lecturer 1 8%
Student > Bachelor 1 8%
Student > Doctoral Student 1 8%
Other 2 17%
Unknown 1 8%
Readers by discipline Count As %
Medicine and Dentistry 7 58%
Pharmacology, Toxicology and Pharmaceutical Science 2 17%
Psychology 1 8%
Biochemistry, Genetics and Molecular Biology 1 8%
Unknown 1 8%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 June 2012.
All research outputs
#10,017,554
of 12,518,737 outputs
Outputs from Clinical, Cosmetic and Investigational Dermatology
#255
of 297 outputs
Outputs of similar age
#84,907
of 119,666 outputs
Outputs of similar age from Clinical, Cosmetic and Investigational Dermatology
#10
of 11 outputs
Altmetric has tracked 12,518,737 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 297 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.6. This one is in the 8th percentile – i.e., 8% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 119,666 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.