| Title |
Current approaches and future directions in the treatment of leprosy
|
|---|---|
| Published in |
Research and reports in tropical medicine, August 2012
|
| DOI | 10.2147/rrtm.s27395 |
| Pubmed ID | |
| Authors |
Sophie M Worobec |
| Abstract |
This review surveys current treatments and future treatment trends in leprosy from a clinical perspective. The World Health Organization provides a multidrug treatment regimen that targets the Mycobacterium leprae bacillus which causes leprosy. Several investigational drugs are available for the treatment of drug-resistant M. leprae. Future directions in leprosy treatment will focus on: the molecular signaling mechanism M. leprae uses to avoid triggering an immune response; prospective studies of the side effects experienced during multiple-drug therapy; recognition of relapse rates post-completion of designated treatments; combating multidrug resistance; vaccine development; development of new diagnostic tests; and the implications of the recent discovery of a genetically distinct leprosy-causing bacillus, Mycobacterium lepromatosis. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 46 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 7 | 15% |
| Researcher | 5 | 11% |
| Student > Bachelor | 5 | 11% |
| Student > Postgraduate | 4 | 9% |
| Professor > Associate Professor | 3 | 7% |
| Other | 8 | 17% |
| Unknown | 14 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 12 | 26% |
| Agricultural and Biological Sciences | 7 | 15% |
| Immunology and Microbiology | 4 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 7% |
| Nursing and Health Professions | 3 | 7% |
| Other | 2 | 4% |
| Unknown | 15 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 August 2012.
All research outputs
#20,823,121
of 25,584,565 outputs
Outputs from Research and reports in tropical medicine
#83
of 101 outputs
Outputs of similar age
#140,428
of 179,468 outputs
Outputs of similar age from Research and reports in tropical medicine
#4
of 5 outputs
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So far Altmetric has tracked 101 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
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