| Title |
Investigation of glucose-modified liposomes using polyethylene glycols with different chain lengths as the linkers for brain targeting
|
|---|---|
| Published in |
International Journal of Nanomedicine, January 2012
|
| DOI | 10.2147/ijn.s23771 |
| Pubmed ID | |
| Authors |
Fulan Xie, Nian Yao, Yao Qin, Qianyu Zhang, Huali Chen, Mingqing Yuan, Jie Tang, Xiankun Li, Wei Fan, Qiang Zhang, Yong Wu, Li Hai, Qin He |
| Abstract |
An intimidating challenge to transporting drugs into the brain parenchyma is the presence of the blood-brain barrier (BBB). Glucose is an essential nutritional substance for brain function sustenance, which cannot be synthesized by the brain. Its transport primarily depends on the glucose transporters on the brain capillary endothelial cells. In this paper, the brain-targeted properties of glucose-modified liposomes using polyethylene glycols with different chain lengths as the linkers were compared and evaluated to establish an optimized drug-delivery system. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 114 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 114 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 22 | 19% |
| Researcher | 18 | 16% |
| Student > Master | 16 | 14% |
| Student > Bachelor | 15 | 13% |
| Student > Doctoral Student | 6 | 5% |
| Other | 11 | 10% |
| Unknown | 26 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 20 | 18% |
| Pharmacology, Toxicology and Pharmaceutical Science | 16 | 14% |
| Agricultural and Biological Sciences | 14 | 12% |
| Biochemistry, Genetics and Molecular Biology | 8 | 7% |
| Medicine and Dentistry | 7 | 6% |
| Other | 17 | 15% |
| Unknown | 32 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 October 2023.
All research outputs
#3,713,898
of 25,394,764 outputs
Outputs from International Journal of Nanomedicine
#250
of 4,122 outputs
Outputs of similar age
#28,353
of 250,240 outputs
Outputs of similar age from International Journal of Nanomedicine
#4
of 80 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,122 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 250,240 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 80 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.