Title |
Review of effects of anti-VEGF treatment on refractive error
|
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Published in |
Eye and Brain, June 2016
|
DOI | 10.2147/eb.s99306 |
Pubmed ID | |
Authors |
Helen A Mintz-Hittner, Megan M Geloneck |
Abstract |
To examine the effect of anti-vascular endothelial growth factor (anti-VEGF) agents on refractive error in the setting of retinopathy of prematurity (ROP) through a review of the literature, a PubMed search was performed of appropriate search terms, and the results of all relevant studies were extracted and compiled. Eleven relevant articles were identified in the literature, totaling 466 eyes, treated with varied anti-VEGF agents (bevacizumab, ranibizumab, and aflibercept) with mean spherical equivalent refractions ranging from +0.75 D to -3.57 D, with prevalence of high myopia ranging from 0 to 35%. Anti-VEGF monotherapy for ROP leads to low levels of myopia, and there may be a differential effect of specific anti-VEGF agents utilized on refractive outcomes. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 29 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 5 | 17% |
Professor > Associate Professor | 3 | 10% |
Professor | 3 | 10% |
Student > Master | 3 | 10% |
Student > Doctoral Student | 2 | 7% |
Other | 7 | 24% |
Unknown | 6 | 21% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 15 | 52% |
Unspecified | 1 | 3% |
Business, Management and Accounting | 1 | 3% |
Agricultural and Biological Sciences | 1 | 3% |
Nursing and Health Professions | 1 | 3% |
Other | 2 | 7% |
Unknown | 8 | 28% |