| Title |
Muscle function in COPD: a complex interplay
|
|---|---|
| Published in |
International Journal of Chronic Obstructive Pulmonary Disease, August 2012
|
| DOI | 10.2147/copd.s28247 |
| Pubmed ID | |
| Authors |
Anna V Donaldson, Matthew Maddocks, Dario Martolini, Michael I Polkey, William D-C Man |
| Abstract |
The skeletal muscles play an essential role in life, providing the mechanical basis for respiration and movement. Skeletal muscle dysfunction is prevalent in all stages of chronic obstructive pulmonary disease (COPD), and significantly influences symptoms, functional capacity, health related quality of life, health resource usage and even mortality. Furthermore, in contrast to the lungs, the skeletal muscles are potentially remedial with existing therapy, namely exercise-training. This review summarizes clinical and laboratory observations of the respiratory and peripheral skeletal muscles (in particular the diaphragm and quadriceps), and current understanding of the underlying etiological processes. As further progress is made in the elucidation of the molecular mechanisms of skeletal muscle dysfunction, new pharmacological therapies are likely to emerge to treat this important extra-pulmonary manifestation of COPD. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Chile | 3 | 43% |
| United Kingdom | 1 | 14% |
| Costa Rica | 1 | 14% |
| Unknown | 2 | 29% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 71% |
| Scientists | 2 | 29% |
Mendeley readers
The data shown below were compiled from readership statistics for 203 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 2 | <1% |
| France | 2 | <1% |
| Chile | 1 | <1% |
| United Kingdom | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 196 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 32 | 16% |
| Student > Ph. D. Student | 28 | 14% |
| Researcher | 26 | 13% |
| Student > Bachelor | 21 | 10% |
| Student > Postgraduate | 14 | 7% |
| Other | 27 | 13% |
| Unknown | 55 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 63 | 31% |
| Nursing and Health Professions | 34 | 17% |
| Agricultural and Biological Sciences | 15 | 7% |
| Sports and Recreations | 7 | 3% |
| Biochemistry, Genetics and Molecular Biology | 3 | 1% |
| Other | 10 | 5% |
| Unknown | 71 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 June 2013.
All research outputs
#6,716,471
of 25,371,288 outputs
Outputs from International Journal of Chronic Obstructive Pulmonary Disease
#745
of 2,577 outputs
Outputs of similar age
#46,293
of 179,161 outputs
Outputs of similar age from International Journal of Chronic Obstructive Pulmonary Disease
#7
of 23 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 2,577 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 179,161 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.