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Lipid nanoparticles for targeted siRNA delivery – going from bench to bedside

Overview of attention for article published in International Journal of Nanomedicine, July 2016
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

twitter
2 tweeters
patent
1 patent

Citations

dimensions_citation
96 Dimensions

Readers on

mendeley
205 Mendeley
Title
<div>Lipid nanoparticles for targeted siRNA delivery &ndash; going from bench to bedside</div>
Published in
International Journal of Nanomedicine, July 2016
DOI 10.2147/ijn.s106625
Pubmed ID
Authors

Victor Kotelianski, Timofei Zatsepin, Yuri Kotelevtsev

Abstract

This review covers the basic aspects of small interfering RNA delivery by lipid nano-particles (LNPs) and elaborates on the current status of clinical trials for these systems. We briefly describe the roles of all LNP components and possible strategies for their improvement. We also focus on the current clinical trials using LNP-formulated RNA and the possible outcomes for therapy in the near future. Also, we present a critical analysis of selected clinical trials that reveals the common logic behind target selection. We address this review to a wide audience, especially to medical doctors who are interested in the application of RNA interference-based treatment platforms. We anticipate that this review may spark interest in this particular audience and generate new ideas in target selection for the disorders they are dealing with.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 205 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Unknown 204 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 48 23%
Student > Master 32 16%
Student > Bachelor 27 13%
Researcher 27 13%
Other 9 4%
Other 22 11%
Unknown 40 20%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 43 21%
Pharmacology, Toxicology and Pharmaceutical Science 35 17%
Agricultural and Biological Sciences 26 13%
Chemistry 19 9%
Engineering 11 5%
Other 28 14%
Unknown 43 21%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 January 2021.
All research outputs
#5,161,339
of 18,263,379 outputs
Outputs from International Journal of Nanomedicine
#509
of 3,292 outputs
Outputs of similar age
#80,002
of 268,011 outputs
Outputs of similar age from International Journal of Nanomedicine
#19
of 128 outputs
Altmetric has tracked 18,263,379 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 3,292 research outputs from this source. They receive a mean Attention Score of 4.0. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 268,011 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 128 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.