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Could lysine supplementation prevent Alzheimer’s dementia? A novel hypothesis

Overview of attention for article published in Neuropsychiatric Disease and Treatment, October 2010
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (56th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

Mentioned by

twitter
3 tweeters
googleplus
1 Google+ user

Citations

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5 Dimensions

Readers on

mendeley
31 Mendeley
Title
Could lysine supplementation prevent Alzheimer’s dementia? A novel hypothesis
Published in
Neuropsychiatric Disease and Treatment, October 2010
DOI 10.2147/ndt.s14338
Pubmed ID
Authors

Rubey

Abstract

There is a growing body of evidence that implicates the herpes simplex type 1 virus (HSV-1) in the development of Alzheimer's dementia (AD). HSV-1 has been found to be present in the cerebrum of the great majority of older adults, and in many of the same areas of the brain that are affected by AD. When active, the virus may contribute to the formation of the neuro-fibrillary tangles and amyloid plaques characteristic of AD. Like AD, HSV-1 encephalitis may cause long term memory loss. HSV-1 replication is suppressed in lysine-rich/arginine - poor environments, and population studies suggest that diets high in lysine and low in arginine may be associated with lower rates of AD. There are no prospective studies of the efficacy of lysine supplementation to prevent or reduce the incidence of AD. Supplementation with adequate doses of lysine could prevent the development of AD.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 3%
Australia 1 3%
Unknown 29 94%

Demographic breakdown

Readers by professional status Count As %
Other 5 16%
Researcher 5 16%
Student > Bachelor 5 16%
Student > Master 5 16%
Student > Postgraduate 4 13%
Other 5 16%
Unknown 2 6%
Readers by discipline Count As %
Medicine and Dentistry 12 39%
Chemistry 3 10%
Psychology 3 10%
Agricultural and Biological Sciences 3 10%
Social Sciences 2 6%
Other 4 13%
Unknown 4 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 October 2019.
All research outputs
#7,536,342
of 14,738,308 outputs
Outputs from Neuropsychiatric Disease and Treatment
#818
of 2,443 outputs
Outputs of similar age
#55,659
of 129,736 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#10
of 28 outputs
Altmetric has tracked 14,738,308 research outputs across all sources so far. This one is in the 48th percentile – i.e., 48% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,443 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 129,736 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.