| Title |
Clinical potential of sodium-glucose cotransporter 2 inhibitors in the management of type 2 diabetes
|
|---|---|
| Published in |
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, August 2012
|
| DOI | 10.2147/dmso.s22545 |
| Pubmed ID | |
| Authors |
Ambika Babu, Kim, Ambika Babu |
| Abstract |
The kidney plays an important role in glucose metabolism, and has been considered a target for therapeutic intervention. The sodium-glucose cotransporter type 2 (SGLT2) mediates most of the glucose reabsorption from the proximal renal tubule. Inhibition of SGLT2 leads to glucosuria and provides a unique mechanism to lower elevated blood glucose levels in diabetes. The purpose of this review is to explore the physiology of SGLT2 and discuss several SGLT2 inhibitors which have clinical data in patients with type 2 diabetes. |
Mendeley readers
The data shown below were compiled from readership statistics for 100 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 1% |
| Spain | 1 | 1% |
| Unknown | 98 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 18 | 18% |
| Student > Bachelor | 12 | 12% |
| Researcher | 11 | 11% |
| Student > Ph. D. Student | 9 | 9% |
| Student > Doctoral Student | 7 | 7% |
| Other | 22 | 22% |
| Unknown | 21 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 37 | 37% |
| Nursing and Health Professions | 7 | 7% |
| Agricultural and Biological Sciences | 7 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 6% |
| Sports and Recreations | 4 | 4% |
| Other | 11 | 11% |
| Unknown | 28 | 28% |