Title |
Adjusting wheal size measures to correct atopy misclassification
|
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Published in |
International Journal of General Medicine, August 2011
|
DOI | 10.2147/ijgm.s22193 |
Pubmed ID | |
Authors |
Hongmei Zhang, Wilfried Karmaus, Jianjun Gan, Weichao Bao, Yan D Zhao, Dewi Rahardja, John W Holloway, Martha Scott, Syed Hasan Arshad |
Abstract |
Skin prick testing (SPT) is fundamental to the practice of clinical allergy identifying relevant allergens and predicting the clinical expression of disease. Wheal sizes on SPT are used to identify atopic cases, and the cut-off value for a positive test is commonly set at 3 mm. However, the measured wheal sizes do not solely reflect the magnitude of skin reaction to allergens, but also skin reactivity (reflected in the size of histamine reaction) and other random or non-random factors. We sought to estimate wheal sizes exclusively due to skin response to allergens and propose gender-specific cutoff points of atopy. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 2 | 20% |
Unknown | 8 | 80% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 3 | 30% |
Professor > Associate Professor | 2 | 20% |
Student > Ph. D. Student | 1 | 10% |
Student > Master | 1 | 10% |
Professor | 1 | 10% |
Other | 0 | 0% |
Unknown | 2 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 3 | 30% |
Agricultural and Biological Sciences | 2 | 20% |
Immunology and Microbiology | 1 | 10% |
Environmental Science | 1 | 10% |
Unknown | 3 | 30% |