Title |
Angiotensin II type 1 receptor antagonists in the treatment of hypertension in elderly patients: focus on patient outcomes
|
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Published in |
Patient related outcome measures, January 2011
|
DOI | 10.2147/prom.s8384 |
Pubmed ID | |
Authors |
Artavazd Tadevosyan, Eric J MacLaughlin, Vardan T Karamyan |
Abstract |
Hypertension in the elderly is one of the main risk factors of cardiovascular and cerebrovascular diseases. Knowledge regarding the mechanisms of hypertension and specific considerations in managing hypertensive elderly through pharmacological intervention(s) is fundamental to improving clinical outcomes. Recent clinical studies in the elderly have provided evidence that angiotensin II type 1 (AT(1)) receptor antagonists can improve clinical outcomes to a similar or, in certain populations, an even greater extent than other classical arterial blood pressure-lowering agents. This newer class of antihypertensive agents presents several benefits, including potential for improved adherence, excellent tolerability profile with minimal first-dose hypotension, and a low incidence of adverse effects. Thus, AT(1) receptor antagonists represent an appropriate option for many elderly patients with hypertension, type 2 diabetes, heart failure, and/or left ventricular dysfunction. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 23 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 6 | 26% |
Student > Bachelor | 3 | 13% |
Researcher | 2 | 9% |
Student > Ph. D. Student | 2 | 9% |
Professor | 1 | 4% |
Other | 1 | 4% |
Unknown | 8 | 35% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 6 | 26% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 9% |
Biochemistry, Genetics and Molecular Biology | 2 | 9% |
Agricultural and Biological Sciences | 2 | 9% |
Sports and Recreations | 1 | 4% |
Other | 2 | 9% |
Unknown | 8 | 35% |