Title |
Risk factors for suicide among patients with schizophrenia: a cohort study focused on cerebrospinal fluid levels of homovanillic acid and 5-hydroxyindoleacetic acid
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Published in |
Neuropsychiatric Disease and Treatment, July 2016
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DOI | 10.2147/ndt.s107178 |
Pubmed ID | |
Authors |
Daniel Neider, Leif H Lindström, Robert Bodén |
Abstract |
The objective of this study was to investigate the association between 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) in cerebrospinal fluid (CSF), bullying, and later suicide among patients with schizophrenia. Ninety-nine patients with schizophrenia were included. Correlations of clinical factors, 5-HIAA and HVA, and later suicide were investigated. Twelve patients committed suicide (12%) during a 28-year follow-up period. Later suicide was correlated to bullying in childhood (P=0.02) and a lower quotient of HVA/5-HIAA in CSF (P<0.05). Suicide in schizophrenia is related to childhood exposedness and CSF neurotransmitter levels. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 20% |
Unknown | 4 | 80% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 60% |
Practitioners (doctors, other healthcare professionals) | 2 | 40% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 3% |
Unknown | 36 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 5 | 14% |
Student > Master | 4 | 11% |
Professor | 3 | 8% |
Researcher | 3 | 8% |
Student > Ph. D. Student | 2 | 5% |
Other | 2 | 5% |
Unknown | 18 | 49% |
Readers by discipline | Count | As % |
---|---|---|
Neuroscience | 6 | 16% |
Psychology | 5 | 14% |
Nursing and Health Professions | 2 | 5% |
Biochemistry, Genetics and Molecular Biology | 1 | 3% |
Agricultural and Biological Sciences | 1 | 3% |
Other | 2 | 5% |
Unknown | 20 | 54% |