| Title |
Potential role of stem cells in severe spinal cord injury: current perspectives and clinical data
|
|---|---|
| Published in |
Stem cells and cloning advances and applications, September 2012
|
| DOI | 10.2147/sccaa.s28477 |
| Pubmed ID | |
| Authors |
Syed AB Paspala, Sandeep K Vishwakarma, Tenneti VRK Murthy, Thiriveedi N Rao, Aleem A Khan |
| Abstract |
Stem cell transplantation for spinal cord injury (SCI) along with new pharmacotherapy research offers the potential to restore function and ease the associated social and economic burden in the years ahead. Various sources of stem cells have been used in the treatment of SCI, but the most convincing results have been obtained with neural progenitor cells in preclinical models. Although the use of cell-based transplantation strategies for the repair of chronic SCI remains the long sought after holy grail, these approaches have been to date the most successful when applied in the subacute phase of injury. Application of cell-based strategies for the repair and regeneration of the chronically injured spinal cord will require a combinational strategy that may need to include approaches to overcome the effects of the glial scar, inhibitory molecules, and use of tissue engineering strategies to bridge the lesion. Nonetheless, cell transplantation strategies are promising, and it is anticipated that the Phase I clinical trials of some form of neural stem cell-based approach in SCI will commence very soon. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| Spain | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 3% |
| United States | 1 | 3% |
| Sweden | 1 | 3% |
| Canada | 1 | 3% |
| Unknown | 27 | 87% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 8 | 26% |
| Student > Bachelor | 6 | 19% |
| Student > Ph. D. Student | 3 | 10% |
| Student > Postgraduate | 3 | 10% |
| Student > Master | 3 | 10% |
| Other | 7 | 23% |
| Unknown | 1 | 3% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 10 | 32% |
| Medicine and Dentistry | 8 | 26% |
| Biochemistry, Genetics and Molecular Biology | 3 | 10% |
| Psychology | 2 | 6% |
| Engineering | 2 | 6% |
| Other | 3 | 10% |
| Unknown | 3 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 November 2013.
All research outputs
#15,048,620
of 25,584,565 outputs
Outputs from Stem cells and cloning advances and applications
#38
of 67 outputs
Outputs of similar age
#109,566
of 188,508 outputs
Outputs of similar age from Stem cells and cloning advances and applications
#2
of 2 outputs
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So far Altmetric has tracked 67 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
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