Title |
Maternal serum endoglin as an early marker of pre-eclampsia in high-risk patients
|
---|---|
Published in |
International Journal of Women's Health, September 2012
|
DOI | 10.2147/ijwh.s35318 |
Pubmed ID | |
Authors |
Tarek Elhawary, Demerdash, Elbendary |
Abstract |
Pre-eclampsia is a potentially serious condition that still accounts for significant morbidity and mortality for the affected mother and neonate. Although the pathogenesis is not fully understood, it is now widely accepted that vascular endothelial dysfunction is the most important and principal event in the pathophysiology of the disease. The aims of our study were to compare serum soluble endoglin levels at week 13 in normotensive pregnant women and in high-risk women, to determine whether the maternal plasma soluble endoglin concentration at 26 weeks is increased in pregnancies that subsequently develop pre-eclampsia, and to identify if soluble endoglin measurement improves the results of screening for pre-eclampsia. |
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