| Title |
Supramolecular micellar nanoaggregates based on a novel chitosan/vitamin E succinate copolymer for paclitaxel selective delivery
|
|---|---|
| Published in |
International Journal of Nanomedicine, December 2011
|
| DOI | 10.2147/ijn.s26305 |
| Pubmed ID | |
| Authors |
He Lian, Jin Sun, Yan Ping Yu, Yan Hua Liu, Wen Cao, Yong Jun Wang, Ying Hua Sun, Si Ling Wang, Zhong Gui He |
| Abstract |
Nowadays, many cytotoxic anticancer drugs exhibit low solubility and poor tumor selectivity, which means that the drug formulation is very important. For example, in the case of paclitaxel (PTX), Cremophor EL(®) (BASF, Ludwigshafen, Germany) needs to be used as a solubilizer in its clinical formulation (Taxol(®), Bristol-Myers Squibb, New York, NY), although it can cause serious side effects. Nanomicellar systems are promising carriers to resolve the above problems, and the polymer chosen is the key element. |
Mendeley readers
The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | 5% |
| Unknown | 18 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 5 | 26% |
| Student > Master | 5 | 26% |
| Student > Ph. D. Student | 2 | 11% |
| Student > Postgraduate | 2 | 11% |
| Professor > Associate Professor | 2 | 11% |
| Other | 1 | 5% |
| Unknown | 2 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 21% |
| Agricultural and Biological Sciences | 4 | 21% |
| Chemistry | 4 | 21% |
| Medicine and Dentistry | 3 | 16% |
| Biochemistry, Genetics and Molecular Biology | 1 | 5% |
| Other | 0 | 0% |
| Unknown | 3 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 December 2013.
All research outputs
#8,261,756
of 25,373,627 outputs
Outputs from International Journal of Nanomedicine
#1,007
of 4,123 outputs
Outputs of similar age
#69,549
of 246,209 outputs
Outputs of similar age from International Journal of Nanomedicine
#18
of 55 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 4,123 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 246,209 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 55 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.