@FatEmperor Haven’t read the article, but the freezer may not be the best idea either way. https://t.co/z50gpibJb0
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
@gerdosi Link did not work. https://t.co/Lmgk9Aw6dU
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
RT @gerdosi: I’m wondering if they got this wrong, too? 🤨 “When stored under aqueous conditions, we found that refrigeration (2°C) kept LN…
@KellyGoodmanPhD @hugh_mankind @fedeperez19 Also, LNPs themselves are not that stable. A lot of research has gone into how to keep them safe in the shelf, and long enough once injected, to deliver mRNA drugs and others. You know that, of course. https://t
@GirardotMarc @JohnBoweActor 2/ Is this the explanation for the bolus?" The separation of phases has been shown to lead to irreversible fusion of nanoparticles and subsequent aggregation"https://t.co/EFx7Wd8gcw.
Has anyone done research into the stability of synthetic lipid nanoparticles under intense heat - ie cooking? Cos it seems stable at freezing, chilled and room temp. They will put mrna in food if they can. Cooking may be mandatory to avoid. https://t.co
Conclusion of newer study on lyophilized siRNA LNPs: "...the addition of trehalose or sucrose to LNP solutions prior to lyophilization facilitated room temperature storage and reconstitution in aqueous buffer without diminishing delivery potency." https:
マイクロチップ反証をしたかっただけなのでこちらには答える義務もないのですが、これだけお答えします。 適切な濃度がないとmRNAを包むナノ粒子が潰れると思いますが、それを実現できる安くて無害な白砂糖を入れているだけでは? stabilityにも関係しているとの事ですし。 https://t.co/RWaGtfpIJ4
There has been talk that the reactogenicity of these rather incredible vaccines might be due to their lipid nanoparticle encapsulation. LNPs can aggregate under improper storage conditions (or so I learned today). This can make them more reactogenic. http
@NicoleKuderer @neerajaiims @OncoAlert @NeliMUlrich @DrChoueiri @montypal @PGrivasMDPhD @VivekSubbiah @ADesaiMD @umangtalking @cdanicas @GGiannarini @pfizer I think this paper explains the sucrose, but it actually raises more questions. This paper says th
@DavidIssadore @MJMitchell_Lab @nytimes Great scientific reviews by @KWhiteheadLab, @yizhoudonglab and other groups on LNP stabilization.... https://t.co/lLRRI01V5h https://t.co/xerMewBJ8B
RT @MtTestudines: Cell cultivation https://t.co/hDqjzx8ViG Encapsulate https://t.co/vLRWKPmjCt Lipid Nanoparticle and Temperature https:/…
Cell cultivation https://t.co/hDqjzx8ViG Encapsulate https://t.co/vLRWKPmjCt Lipid Nanoparticle and Temperature https://t.co/NmhJMqg5Q1 https://t.co/bZPWhwjh9V https://t.co/5JafD9sgq3 https://t.co/KYSShisfv7
RT @KWhiteheadLab: How to stabilize LNPs for long term storage - congrats to my student @beccaleeball on her 2nd first author paper https:…
RT @KWhiteheadLab: How to stabilize LNPs for long term storage - congrats to my student @beccaleeball on her 2nd first author paper https:…
RT @KWhiteheadLab: How to stabilize LNPs for long term storage - congrats to my student @beccaleeball on her 2nd first author paper https:…
RT @KWhiteheadLab: How to stabilize LNPs for long term storage - congrats to my student @beccaleeball on her 2nd first author paper https:…
How to stabilize LNPs for long term storage - congrats to my student @beccaleeball on her 2nd first author paper https://t.co/KPm3zUhI2o